Searching for the clinical effects of colloid solutions that used to increasing the oncotic pressure of priming solutions at the cardiopulmonary bypass, 29 patients(who were diagnosised as simple VSD around 10kg of body weight and scheduled to
be
operated from June 1990 to December 1990 at Sejong General Hospital) were divided randomly and prospectively to the two groups : A group (15) was received 4gm% albumin as addition to the priming solutions and B Group (14) the same amount of
Ringer's
lactated solution.
34 clinical parameters (Body weight, sex, age, body surface area, Qp/Qs, pulmonary arterial pressure, cardiopulmonary bypass time, anesthetic time, intraoperatively infused crystalloid and colloid amount, hemoglobin, hematocrit, serum sodium
concentration, serum osmolarity, urine osmolarity, urine specific gravity, serum concentration, serum osmolarity, urine osmolarity, urine specific gravity, serum protein, serum osmolarity, urine osmolarity, urine specific gravity, serum protein,
serum
albumin concentration, urine output, central venous pressure, postoperatively infused colloid amount, immedediate post inspiratory pressure, cardiac index, blood pressure and pump flow during cardiopulmonary bypass, inotropic assist, diuretics,
extubation period, total drain amount, duration of ICU) were measured and compaired between the two groups.
There were no differences of preoperative and operative clinical parameters. And postoperatively, practically there were n nearly differences at the clinical outcomes between the two groups, but some parameters (cardiac index, PIP, BP and
pumpflow
during CPB, etc) contributed to being preferable to the Group A at certain times (P<0.05).
Conclusively, it might be thought that the priming solution of cardiopulmonary bypass added by colloid solution had some beneficial effects on the patients, especially younger and associated with complex anomaly to be expected taken longer time
of
cardiopulmonary bypass, and more studies about the neonatal and complex anomaly cases were needed in that points.
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